Thermo Fisher Scientific MARCH2 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MARCH2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MARCH2,uniProtId:Q9P0N8-1,ncbiNodeId:9606,antigenRange:198-246,antigenLength:246,antigenImageFileName:PA5-53121_MARCH2_Q9P0N8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53121_MARCH2_Q9P0N8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643763

Product Specific Information

Immunogen sequence: RYHCQLYSEW RKTNQKVRLK IREADSPEGP QHSPLAAGLL KKVAEETPV

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.

Target Information

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.