Thermo Fisher Scientific PNK Recombinant Rabbit Monoclonal Antibody (JE64-21)
PNK 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. HEK293 세포에서 발현되었으며, Protein A로 정제된 액상 형태입니다. DNA 손상 복구 연구에 유용하며, 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE64-21 |
| Immunogen | Synthetic peptide within Human PNKP aa 51–100/521 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931222 |
Target Information
Anti-human Polynucleotide Kinase (PNK) Monoclonal Antibody recognizes PNK, a 57 kDa nuclear enzyme involved in DNA strand repair processes during replication and recombination or in response to DNA damage.
PNK acts on DNA termini for phosphorylation and dephosphorylation at 5′-hydroxy and 3′-phosphate ends.
In human cells, PNK associates with nuclear proteins to prepare DNA termini for DNA polymerase-β and DNA ligase III actions.
PNK is essential for maintaining genetic stability in human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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