Thermo Fisher Scientific RASA1 Polyclonal Antibody
RASA1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ICC/IF, Flow Cytometry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. 재구성 시 500 µg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| Flow Cytometry (Flow) | 1–3 µg/1×10⁶ cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human RASA1 (1018–1047aa: AQQHVLKKLLAITELLQQKQNQYTKTNDVR) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2747030 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
TACC1 is located on the 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members (TACC1, TACC2, and TACC3) map closely to the corresponding FGFR1, FGFR2, and FGFR3 genes on chromosomes 4, 8, and 10. Since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. TACC1 contains a conserved C-terminal region similar to the Drosophila homolog D-TACC, which is necessary for normal spindle function. Mammalian TACC proteins appear to interact with centrosomes and microtubules in a similar manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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