Thermo Fisher Scientific ATF4 Monoclonal Antibody (2A6F12)
ATF4 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, IHC, ELISA에 적합. 정제된 재조합 인간 ATF4 단백질(AA 212-351)을 면역원으로 사용. Protein G 정제, 액상 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A6F12 |
| Immunogen | Purified recombinant fragment of human ATF4 (AA: 212–351) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090910 |
Target Information
This gene encodes a transcription factor originally identified as a widely expressed mammalian DNA-binding protein that binds a tax-responsive enhancer element in the LTR of HTLV-1. It was also characterized as cAMP-response element binding protein 2 (CREB-2).
The encoded protein belongs to a family of DNA-binding proteins including the AP-1, CREB, and CREB-like transcription factors. These proteins share a leucine zipper region for protein-protein interactions and a basic amino acid stretch functioning as a DNA-binding domain.
Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 within a region containing a large inverted duplication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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