Thermo Fisher Scientific RASSF1 Polyclonal Antibody
RASSF1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인체 시료에 반응합니다. IHC(P)에서 1:200–1:500 희석으로 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer(40% glycerol, 0.02% sodium azide)에 보관됩니다. 암 연구 등 종양 억제 관련 연구에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RASSF1. Recombinant protein control fragment (Product # RP-98331) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646340 |
Product Specific Information
Immunogen sequence:
KFTCHYRCRA LVCLDCCGPR DLGWEPAVER DTNVDEPVEW ETPDLSQAEI EQKIKEYNAQ INSNLFMSLN KDG
Sequence identity:
- Mouse: 89%
- Rat: 90%
Target Information
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of various cancers, suggesting a tumor suppressor function. Inactivation of this gene is correlated with hypermethylation of its CpG-island promoter region. The encoded protein interacts with DNA repair protein XPA and inhibits the accumulation of cyclin D1, inducing cell cycle arrest. Seven alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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