Thermo Fisher Scientific SPIRE1 Polyclonal Antibody
Human SPIRE1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 세포 내 소포 수송 및 세포 분열 관련 연구에 적합.
- 카탈로그번호
- PA559274
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPIRE1. Recombinant protein control fragment (Product #RP-98283). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647868 |
Product Specific Information
Immunogen sequence:
LEEIKAERKL RPVSPEEIRR SRLDVTTPES TKNLVESSMV NGGLTSQTKE NGLSTSQQVP AQRKKLLRAP TLAELDSSES EEETLHK
Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 83%
Target Information
Acts as an actin nucleation factor, remaining associated with the slow-growing pointed end of new filaments. Involved in intracellular vesicle transport along actin fibers, linking actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Also required for normal cleavage furrow formation and polar body extrusion during female germ cell meiosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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