Thermo Fisher Scientific ZBTB5 Polyclonal Antibody
ZBTB5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Rabbit IgG 호스트 기반으로 제작되었으며 Western blot에 적합합니다. 액상 형태로 제공되며 4°C에서 보관합니다. 세포 주기 조절 관련 연구용으로 사용됩니다.
- 판매단위
- pk
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Thermo Fisher Scientific ZBTB5 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between 525 and 575 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The ZBTB family of proteins comprises diverse zinc finger proteins that also contain a BTB (BR-C, ttk, and bab) domain.
ZBTB5 was identified through sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein.
It binds DNA and can directly repress transcription of the cell cycle arrest gene p21.
ZBTB5 interacts with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter.
ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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