Thermo Fisher Scientific PCDH1 Polyclonal Antibody
Thermo Fisher Scientific의 PCDH1 Polyclonal Antibody는 인간 PCDH1 단백질을 인식하는 토끼 유래 항체입니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, 고순도의 Protein A 및 항원 친화 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA535091
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- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 179–206 amino acids from the N-terminal region of human PCDH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552401 |
Target Information
Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. It belongs to the delta1-protocadherin family, which includes protocadherin-1, -7, -9, and -11(X/Y). These proteins possess seven extracellular cadherin-repeats, a transmembrane domain, and a cytoplasmic domain, and can exist in short or long isoforms.
PCDH1 expression is temporally and spatially regulated, playing roles in both early development and mature tissues. In mice, it is expressed in the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and seminal gland. In humans, PCDH1 is a susceptibility gene for Bronchial Hyperresponsiveness and is expressed on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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