Thermo Fisher Scientific GPR116 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human GPR116. Validated for IHC (Paraffin) at 6 µg/mL. Supplied as liquid, 1 mg/mL concentration. Suitable for research use in studying G protein-coupled receptor signaling and cellular acid-base regulation.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 6 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GPR116 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2279242 |
Product Specific Information
PA1-32512 detects GPCR GPR116 from human samples.
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, form a superfamily of proteins involved in various stimulus-response pathways. These receptors translate extracellular signals into intracellular signals through G protein activation and respond to a variety of signaling molecules, such as hormones and neurotransmitters.
GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein containing one SEA domain, one GPS domain, and three Ig-like domains, belonging to the GPR family. It exists as a disulfide-linked homodimer at the cell surface and has multiple alternatively spliced isoforms. GPR116 is thought to play a role in regulating and maintaining proper acid-base balance within the cell.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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