Thermo Fisher Scientific FGFR1 Polyclonal Antibody, FITC
FGFR1 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, IP 등에 사용 가능. Human 및 Rat 시료에 반응하며, 친화 크로마토그래피로 정제됨. 형광 특성은 498/517 nm으로 세포 분석 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 640–690 on human basic fibroblast growth factor receptor protein 1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor (FGFR) family, which includes four membrane-spanning tyrosine kinases (FGFR1–4) serving as high-affinity receptors for 17 growth factors (FGF1–17).
These receptors are involved in critical biological processes such as mesoderm induction, cell growth and migration, organ formation, and bone development.
FGFR1 has multiple splice variants expressed differently during embryonic and adult stages.
Mutations or defects in FGFR1 are associated with several diseases, including Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, non-syndromic trigonocephaly, Jackson-Weiss syndrome, and Antley-Bixler syndrome.
Chromosomal aberrations involving FGFR1 are linked to stem cell myeloproliferative disorders and stem cell leukemia/lymphoma syndromes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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