Thermo Fisher Scientific RPGR Polyclonal Antibody
Rabbit에서 유래한 RPGR 단백질 인식용 polyclonal antibody. 재조합 인간 RPGR 항원을 면역원으로 사용. 액상 형태, 0.3 mg/mL 농도. 단기 4°C, 장기 -20°C 보관. X-연관 망막색소변성 연구 등 RPGR 관련 연구용.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RPGR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664296 |
Product Specific Information
Immunogen sequence:
PFFGNLPDRGM NTESEENKDF VKKRESCKQD VIFDSERESV EKPDSYMEGA SESQQGIADG FQQPEAIEFS SGEKEDDEVE TDQNIRYGRK LIEQG
- Highest antigen sequence identity to the following orthologs:
- Mouse: 48%
- Rat: 29%
Target Information
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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