Thermo Fisher Scientific HSPB8 Polyclonal Antibody
HSPB8 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS, 40% 글리세롤에 보관됩니다. 인간 시료 반응성, 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HSPB8. Recombinant protein control fragment (Product #RP-91460) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856222 |
Product Specific Information
Immunogen sequence:
LLDDGFGMDP FPDDLTASWP DWALPRLSSA WPGTLRSGMV PRGPTATARF GVPAEGRTPP PFPGEPWKVC VNVHSFKPEE LMVKTKDGYV EVSGKHEEKQ QEGGIVSKNF TKKIQLP
Target Information
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conserved alpha-crystallin domain at the C-terminal region. Expression of this gene is induced by estrogen in estrogen receptor-positive breast cancer cells. This protein functions as a chaperone in association with Bag3, a stimulator of macroautophagy. It is involved in the regulation of cell proliferation, apoptosis, and carcinogenesis. Mutations in this gene have been associated with neuromuscular diseases, including Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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