Thermo Fisher Scientific Phospho-LEF1 (Ser42) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phosphorylated LEF1 (Ser42). Validated for Western blot (1:500–1:1,000). Involved in Wnt signaling and cancer research. Supplied as liquid, 1 mg/mL, stored at -20°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human LEF-1 around the phosphorylation site of Ser42 (E-I-SP-H-P) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555259 |
Target Information
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway and may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-38664_LEF1_Q9UJU2-1_Rabbit.svg, PA5-38664_LEF1_Q9UJU2-1_Rabbit_PDP.jpeg)
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