Thermo Fisher Scientific PCBP1 Polyclonal Antibody
PCBP1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간 및 랫트 반응성. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS buffer(pH 7.3)에 0.5% BSA 포함. 연구용으로만 사용.
- 카탈로그번호
- PA519408
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SIQGQHTISPLD) corresponding to internal amino acids of PCBP1 (aa 223–234) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979322 |
Product Specific Information
- This antibody is predicted to react with canine and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes.
The protein encoded by this gene appears to be multifunctional. Along with PCBP-2 and hnRNPK, it corresponds to major cellular polydomains involved in RNA binding.
Together with PCBP-2, it functions as a translational coactivator of poliovirus RNA via sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5′-terminal cloverleaf structure.
It has also been implicated in translational control of 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.
The encoded protein is suggested to play a role in formation of a sequence-specific alpha-globin mRNP complex associated with alpha-globin mRNA stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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