Thermo Fisher Scientific NCoR2 Monoclonal Antibody (1212)
인간 및 비인간 영장류 반응성을 가진 NCoR2 단클론 항체. Western blot, IHC(F), IP, ChIP 등 다양한 실험에 적용 가능. SMRT 단백질 유래 합성 펩타이드 면역원 사용. Protein G 정제, 1 mg/mL 농도의 액상 형태로 제공. 연구용 전용 시약.
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Thermo Fisher Scientific NCoR2 Monoclonal Antibody (1212)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Immunoprecipitation (IP) | Assay-dependent |
| ChIP assay (ChIP) | 3 µg / 1×10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1212 |
| Immunogen | A synthetic peptide from the human SMRT protein corresponding to amino acids 994–1005 (ASASDPHREKTQ) coupled to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787216 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: HBL100.
Target Information
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily.
Associated proteins known as coactivators and corepressors modulate transcriptional activity of these nuclear receptors.
Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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