Thermo Fisher Scientific Myotilin Polyclonal Antibody
Myotilin 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot, ICC/IF, ELISA에 사용 가능하며, 고순도의 Affinity Chromatography 정제 항체입니다. 근육 수축 관련 단백질 연구에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 259–314 of human MYOT (NP_001129412.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855419 |
Product Specific Information
Immunogen sequence:
RPNQTLPAPK QLRVRPTFSK YLALNGKGLN VKQAFNPEGE FQRLAAQSGL YESEEL
Target Information
This gene encodes a cytoskeletal protein that plays a significant role in the stability of thin filaments during muscle contraction. The protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene are associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants have been described, though the full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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