Thermo Fisher Scientific NAIF1 Polyclonal Antibody
Thermo Fisher Scientific의 NAIF1 Polyclonal Antibody는 인간 NAIF1 단백질을 검출하는 고품질 항체로, WB 및 IHC(P) 실험에 적합합니다. Rabbit IgG 기반의 비결합 액상 항체이며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of Human NAIF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635694 |
Product Specific Information
The antibody detects endogenous levels of total NAIF1 protein.
Target Information
Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region.
NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken, and frog, and shares no obvious homology to any known genes or proteins.
NAIF1 is predominantly localized in the nucleus. Overexpression of NAIF1 inhibits cell growth and induces apoptosis. Furthermore, NAIF1 transfection causes decreases in mitochondrial membrane potential and caspase-3 activation.
In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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