Thermo Fisher Scientific MUC20 Polyclonal Antibody
MUC20 단백질의 내인성 수준을 검출하는 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC(Paraffin) 실험에 적합하며, Human 및 Mouse 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer에 40% glycerol과 sodium azide를 포함합니다.
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- PA550238
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human mucin 20 (cell surface associated) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635691 |
Product Specific Information
The antibody detects endogenous levels of total MUC20 protein.
Target Information
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier.
The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted.
The C terminus of this protein associates with the multifunctional docking site of the MET proto-oncogene and suppresses activation of some downstream MET signaling cascades.
The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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