Thermo Fisher Scientific VIM Monoclonal Antibody (OTI7A9), TrueMAB
인간 Vimentin 단백질을 인식하는 Mouse IgG1 단클론 항체로, Luminex 등 다양한 어플리케이션에 사용 가능. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 함. 친화 크로마토그래피로 정제된 액상 항체로, -20°C에서 보관.
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Applications
- Luminex (LUM): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A9 |
| Immunogen | Full length human recombinant protein of human VIM produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During development, vimentin is replaced by tissue-specific IFPs. Vimentin is also implicated in the regulation of steroid synthesis through its role in cholesterol-containing lipid droplet storage and transport. Phosphorylation of vimentin by protein kinases leads to filament breakdown and cytoskeletal rearrangements that facilitate cholesterol transport into mitochondria, enhancing steroidogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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