Thermo Fisher Scientific P2X3 Polyclonal Antibody
P2X3 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 액상 형태, 1 mg/mL 농도, PBS + 50% 글리세롤 보존. ATP 수용체 연구 및 통증 신호 전달 기전 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human P2RX3 (Accession P56373), corresponding to amino acid residues D379–H397 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900342 |
Product Specific Information
Antibody detects endogenous levels of total P2X3.
Target Information
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses and also participates in pathways controlling urinary bladder volume reflexes. The development of selective antagonists for this receptor may have therapeutic potential in pain relief and in the treatment of disorders of urine storage.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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