Thermo Fisher Scientific ERAS Polyclonal Antibody
ERAS 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC(P)에서 1:100 희석으로 검증됨. 합성 펩타이드(178-195 aa) 면역원 사용. 비결합형 액상 형태로 제공되며 -20°C 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (178 VETSAKTRQGVEEAFSLL 195) of ERAS protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2540765 |
Target Information
The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein.
The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein.
ERAS protein has less than 50% amino acid identity with H-Ras, another member of the Ras family, but the key domains essential for Ras function are highly conserved.
The protein also contains amino acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells.
Human ERAS gene is localized in the chromosomal region Xp11.23.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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