Thermo Fisher Scientific TYRO3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing TYRO3 protein. Validated for Western blot at 0.25–1 µg/mL. Suitable for research on cell signaling, survival, and differentiation. Supplied as liquid form, 0.5 mg/mL, stored at 4°C short term or -20°C long term.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.25–1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (494 TLDSLGISDELKEKLEDV 511) of TYRO3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2540769 |
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to ligands such as TULP1 or GAS6. It regulates physiological processes including cell survival, migration, and differentiation. Ligand binding induces dimerization and autophosphorylation of TYRO3, creating docking sites for downstream signaling molecules. Upon activation, TYRO3 contributes to neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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