Thermo Fisher Scientific CD116 Monoclonal Antibody (4H1), PE, eBioscience
인간 CD116(GM-CSF 수용체 α-체인)을 인식하는 단클론 항체로, PE 형광표지되어 유세포분석에 최적화됨. 4H1 클론, 마우스 IgG1, kappa 아이소타입. 친화 크로마토그래피 정제, 4°C 암소 보관. 연구용으로만 사용.
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Thermo Fisher Scientific CD116 Monoclonal Antibody (4H1), PE, eBioscience™
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.5 µg)/test
Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H1 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10717400 |
Additional Formats:
Product Specific Information
The 4H1 monoclonal antibody reacts with the human CD116 molecule, the alpha subunit of GM-CSF receptor. The alpha subunit associates with the common beta chain (CD131) to form the high-affinity receptor for GM-CSF.
The GM-CSFR alpha chain is expressed by granulocytes, monocytes, endothelial cells, fibroblasts, and some tumor cells.
Applications Reported: 4H1 has been reported for use in flow cytometric analysis.
Applications Tested: Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells.
Recommended usage: 5 µL (0.5 µg) per test (100 µL final volume; 10⁵–10⁸ cells/test).
Spectral Properties:
Excitation: 488–561 nm; Emission: 578 nm
Laser Compatibility: Blue, Green, Yellow-Green
Filtration: 0.2 µm post-manufacturing filtered
Target Information
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2 (GM-CSF), a cytokine controlling the production, differentiation, and function of granulocytes and macrophages.
This gene resides in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encode different isoforms, including membrane-bound and soluble forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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