Thermo Fisher Scientific HDAC7 Monoclonal Antibody (PCRP-HDAC7-1B6)
HDAC7 단백질을 인식하는 Mouse monoclonal 항체로, Flow Cytometry 및 Peptide Array에 사용 가능. HeLa 세포에서 양성 대조군으로 사용되며, 핵 내 위치한 HDAC7 단백질 검출에 적합. Protein A/G 정제, 4°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-HDAC7-1B6 |
| Immunogen | Recombinant full-length human HDAC7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: HeLa cells
- Cellular Location: Nucleus
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the mouse HDAC7 gene, whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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