Thermo Fisher Scientific SLC39A4 Polyclonal Antibody
SLC39A4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 마우스 반응성 및 다양한 응용(WB, IHC, Flow)에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동결 건조 형태로 제공. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse SLC39A4 (Met1–Tyr337) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607121 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
The zinc transporter ZIP4, also known as SLC39A4, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation. ZIP4 was initially identified as a zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in dietary zinc absorption. Aberrant expression of ZIP4 has been linked to cancer progression, particularly pancreatic and hepatocellular carcinomas, where it can repress apoptosis, enhance cell cycle progression, and increase migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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