Thermo Fisher Scientific TSPAN8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 110-200 of human TSPAN8 (NP_0046071) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TSPAN8,uniProtId:P19075-1,ncbiNodeId:9606,antigenRange:110-200,antigenLength:237,antigenImageFileName:PA5-89125_TSPAN8_P19075-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89125_TSPAN8_P19075-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.96 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805370

Product Specific Information

Immunogen sequence: KSKSDRIVNE TLYENTKLLS ATGESEKQFQ EAIIVFQEEF KCCGLVNGAA DWGNNFQHYP ELCACLDKQR PCQSYNGKQV YKETCISFIK D; Positive Samples: Mouse lung, Rat lung; Cellular Location: Membrane, Multi-pass membrane protein

Target Information

TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein that belongs to the tetraspanin family of transmembrane proteins and is thought to play a role in signal transduction events that influence cell development, activation, growth and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal and pancreatic cancers, strongly suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.