Thermo Fisher Scientific CD97 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 240-435 of human CD97 (NP_001775.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD97,uniProtId:P48960-1,ncbiNodeId:9606,antigenRange:240-435,antigenLength:835,antigenImageFileName:PA5-120871_CD97_P48960-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120871_CD97_P48960-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.82 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914443

Product Specific Information

Positive test controls include: HepG2, Jurkat, Mouse lung, Rat liver. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein, Secreted, extracellular space.

Immunogen sequence: NLEDIMRILA KSLPKGPFTY ISPSNTELTL MIQERGDKNV TMGQSSARMK LNWAVAAGAE DPGPAVAGIL SIQNMTTLLA NASLNLHSKK QAELEEIYES SIRGVQLRRL SAVNSIFLSH NNTKELNSPI LFAFSHLESS DGEAGRDPPA KDVMPGPRQE LLCAFWKSDS DRGGHWATEG CQVLGSKNGS TTCQCS

Target Information

CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.