Thermo Fisher Scientific CD97 Polyclonal Antibody
CD97 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. Western blot 및 ELISA에 적합. 고순도 친화성 크로마토그래피 정제. 세포막 단백질 검출용 연구 전용 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 240–435 of human CD97 (NP_001775.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.82 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914443 |
Product Specific Information
- Positive test controls: HepG2, Jurkat, Mouse lung, Rat liver
- Localization: Cell membrane, Multi-pass membrane protein, Secreted, extracellular space
Immunogen sequence:
NLEDIMRILA KSLPKGPFTY ISPSNTELTL MIQERGDKNV TMGQSSARMK LNWAVAAGAE DPGPAVAGIL SIQNMTTLLA NASLNLHSKK QAELEEIYES SIRGVQLRRL SAVNSIFLSH NNTKELNSPI LFAFSHLESS DGEAGRDPPA KDVMPGPRQE LLCAFWKSDS DRGGHWATEG CQVLGSKNGS TTCQCS
Target Information
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation.
It is produced in alternatively spliced forms, and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage.
Interaction of CD97 on leukocytes and CD55 on vessel cells facilitates leukocyte activation and migration into tissues. CD97 also plays roles in tumor migration, invasiveness, T cell regulation, and peripheral granulocyte homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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