
Thermo Fisher Scientific SGK1 Polyclonal Antibody
Goat polyclonal antibody targeting SGK1 for IHC and ELISA applications. Recognizes human SGK1 (aa 390–403). Supplied as liquid, unconjugated, 0.5 mg/mL concentration. Ideal for research on cellular stress response and survival pathways.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-TEEPVPNSIGKSPD (aa 390–403) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933125 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-142477_SGK1_O00141-1_Goat.svg, PA5-142477_SGK1_O00141-1_Goat_PDP.jpeg)
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