Thermo Fisher Scientific eEF1G Polyclonal Antibody
Rabbit polyclonal antibody against human eEF1G for WB and IP applications. Recognizes C-terminal region (residues 400–437). Predicted to react with bovine, horse, and pig. Supplied as liquid, 0.2 mg/mL, stored at 4°C. For research use only.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 400 and the C-terminus (residue 437) of human Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G, UniProt ID: P26641-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine, Horse, and Pig
Target Information
EF-1 (elongation factor-1) is a multi-protein complex responsible for the delivery of aminoacyl-tRNAs to the ribosome. EF-1 gamma (EEF1G), also known as GIG35, is a 437 amino acid subunit of the EF-1 complex. It is expressed in stomach, pancreas, brain, lung, kidney, intestine, liver, and spleen. EF-1 gamma contains an N-terminal Glutathione transferase domain, which may anchor the complex to cellular components, and plays a role in assembling multiprotein complexes containing aminoacyl-tRNA synthetases. Increased expression of EF-1 gamma has been associated with pancreatic cancer, suggesting its potential involvement in oncogenic transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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