Thermo Fisher Scientific TIMP1 Recombinant Rabbit Monoclonal Antibody (004)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin–free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Human TIMP1.

Target Information

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that forms one-to-one complexes with target metalloproteinases such as collagenases, irreversibly inactivating them by binding to their catalytic zinc cofactor.
TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16.
It also functions as a growth factor that regulates cell differentiation, migration, and cell death, and activates signaling cascades via CD63 and ITGB1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.