Thermo Fisher Scientific IL-9 Recombinant Rabbit Monoclonal Antibody (030)

Applications

ELISA

• Tested Dilution: 1:5,000–1:10,000
• Publications: N/A

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening for optimal clones.
Advantages include:

• Superior specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the larger rabbit immune repertoire

This antibody has specificity for Rat IL-9.

Target Information

Interleukin 9 (IL-9) is produced by activated T helper 2 (Th2) lymphocytes. IL-9 regulates various cell types involved in Th2-associated asthma responses, including B and T lymphocytes, mast cells, eosinophils, and epithelial cells.
Mouse IL-9 cDNA encodes a 144 amino acid precursor protein with an 18 amino acid signal peptide, forming a mature cysteine-rich protein (~14 kDa). Native mouse IL-9 is heavily glycosylated.
TGF-β has been reported to play an important role in differentiation of IL-17-producing T helper cells and inducible regulatory T cells by reprogramming Th2 cells to secrete IL-9, thereby driving differentiation of Th9 cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.