Thermo Fisher Scientific SCAMP2 Monoclonal Antibody (OTI2F1), TrueMAB
SCAMP2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 특이적 반응성을 가지며, 고순도 친화 크로마토그래피로 정제. PBS/BSA/glycerol 저장용액에 포함되어 -20°C에서 안정적으로 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F1 |
| Immunogen | Full length human recombinant protein of human SCAMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking.
In fibroblasts, SCAMPs are concentrated in compartments for recycling cell surface receptors and endocytosis.
In neurons, SCAMPs associate with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs consist of four central transmembrane regions and a cytoplasmic tail.
Among five known SCAMPs, SCAMPs 1–3 have cytoplasmic N-terminal regions with NPF repeats that interact with EH domain proteins, functioning in budding of transport vesicles from the plasma membrane or Golgi complex.
SCAMPs 4 and 5 lack NPF repeats. SCAMPs 1–4 are ubiquitously coexpressed, while SCAMP 5 is detectable only in the brain and expressed late in development, coinciding with mature synapse expansion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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