Thermo Fisher Scientific GRB14 Polyclonal Antibody
GRB14 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 액상 형태로 제공됩니다. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GRB14 (Accession Q14449), corresponding to amino acid residues F90–K140 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851046 |
Product Specific Information
Antibody detects endogenous levels of total GRB14.
Target Information
The GRB14 gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. It belongs to a small family of adapter proteins known to interact with receptor tyrosine kinases and signaling molecules. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling, particularly on insulin receptor signaling. GRB14 may play a role in pathways regulating growth and metabolism. Transcript variants have been reported, but their full-length natures have not yet been determined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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