Thermo Fisher Scientific Actin, Muscle Specific (Muscle Cell Marker) Monoclonal Antibody (HHF35)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

0.25-0.5 µg/mL

-

Immunocytochemistry (ICC/IF)

1-2 µg/mL

-

Flow Cytometry (Flow)

1-2 µg/10^6 cells

-

Product Specifications

Species Reactivity

Dog, Chicken, Cat, Human, Mouse, Rabbit, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

HHF35

Immunogen

SDS extract of human myocardium. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Actin Muscle,uniProtId:P62736-1,ncbiNodeId:9606,antigenRange:1-377,antigenLength:377,antigenImageFileName:MSM1-445-P0_Actin_Muscle_P62736-1_House_mouse.svg,antigenImageFileNamePDP:MSM1-445-P0_Actin_Muscle_P62736-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:Actin Muscle,uniProtId:P63261-1,ncbiNodeId:9606,antigenRange:1-375,antigenLength:375,antigenImageFileName:MSM1-445-P0_Actin_Muscle_P63261-1_House_mouse.svg,antigenImageFileNamePDP:MSM1-445-P0_Actin_Muscle_P63261-1_House_mouse_PDP.jpeg,sortOrder:2},{targetFamily:Actin Muscle,uniProtId:P63267-1,ncbiNodeId:9606,antigenRange:1-376,antigenLength:376,antigenImageFileName:MSM1-445-P0_Actin_Muscle_P63267-1_House_mouse.svg,antigenImageFileNamePDP:MSM1-445-P0_Actin_Muscle_P63267-1_House_mouse_PDP.jpeg,sortOrder:3},{targetFamily:Actin Muscle,uniProtId:P68032-1,ncbiNodeId:9606,antigenRange:1-377,antigenLength:377,antigenImageFileName:MSM1-445-P0_Actin_Muscle_P68032-1_House_mouse.svg,antigenImageFileNamePDP:MSM1-445-P0_Actin_Muscle_P68032-1_House_mouse_PDP.jpeg,sortOrder:4},{targetFamily:Actin Muscle,uniProtId:P68133-1,ncbiNodeId:9606,antigenRange:1-377,antigenLength:377,antigenImageFileName:MSM1-445-P0_Actin_Muscle_P68133-1_House_mouse.svg,antigenImageFileNamePDP:MSM1-445-P0_Actin_Muscle_P68133-1_House_mouse_PDP.jpeg,sortOrder:5}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.