Thermo Fisher Scientific CNR2 Polyclonal Antibody
인간 CNR2/CB2 단백질을 인식하는 토끼 폴리클로날 항체. 파라핀 포매 조직의 면역조직화학(IHC) 실험에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 단기 보관 또는 -20°C 장기 보관 가능. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 17 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human CNR2 / CB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550822 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%)
Marmoset (95%)
Monkey (90%)
Elephant (85%)
Bat, Bovine, Horse (80%)
Target Information
Cannabinoids exert their physiological effects through two G protein-coupled receptors: cannabinoid receptor 1 (CB1) and CB2.
Both receptors inhibit adenylyl cyclase and stimulate mitogen-activated protein kinase (MAPK).
CB1 receptors modulate ion channels via direct G-protein interactions, while CB2 is primarily expressed in the immune system, with potential presence in the central nervous system including the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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