Thermo Fisher Scientific Human SRC3 (aa 3-15) Synthetic Peptide

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

purified

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

PEP-049 is a 14 amino acid synthetic peptide whose sequence corresponds to residues 3-15 of human AIB1. The sequence of this peptide is (amino to carboxy terminus): G3-L-G-E-N-L-D-P-L-A-S-D-S15-C (The C-terminal cysteine has been added to facilitate conjugation and is not a part of the native human AIB1 sequence).

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and AIB1, catalog # PA1-845. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

Reconstitute with 0.1 mL of distilled water.

Target Information

AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kDa. The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines. AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.