Thermo Fisher Scientific CD5 Monoclonal Antibody (YKIX322.3), FITC
Thermo Fisher Scientific의 CD5 단클론 항체(YKIX322.3), FITC 형은 개의 CD5 항원을 인식하며 FACS 분석에 적합합니다. FITC 형광 표지로 498/517 nm에서 검출되며, T 세포 및 NK 세포 표면 단백질 연구에 활용됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat–1:10
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | YKIX322.3 |
| Immunogen | Concanavilin A activated canine peripheral blood cells |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_928955 |
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
Rat anti-Dog CD5 antibody, clone YKIX322.3 recognizes canine CD5, a 67 kDa cell surface type 1 transmembrane glycoprotein also known as lymphocyte antigen T1, Ly-1, or Leu-1.
CD5 is expressed on the surface of T-cells and thymocytes, and also at low levels on NK cells (Huang et al., 2008).
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein.
It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas.
CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.
CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes.
In lymph nodes, reactivity is mainly observed in T cell areas.
Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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