Thermo Fisher Scientific SRPX2 Polyclonal Antibody
SRPX2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 신경 및 암 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the amino terminus of human SRPX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Refrigerate at 2–8°C for up to 3 months; for long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153021 |
Product Specific Information
- Suggested positive control: human lung tissue lysate
- PA5-20844 can be used with blocking peptide PEP-0958
Target Information
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain. Mutations in this gene are associated with epilepsy, speech dyspraxia, mental retardation, and cognitive disorders.
SRPX2 also mediates angiogenesis and acts as a ligand for the urokinase-type plasminogen activator, promoting endothelial cell migration. Overexpression in gastric cancer enhances phosphorylation of focal adhesion kinase, suggesting SRPX2 as a potential target for metastatic cancer treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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