Thermo Fisher Scientific ZDHHC-18 Polyclonal Antibody
ZDHHC-18 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ICC, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human ZDHHC-18 (amino acids 265–360) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4) with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zinc-finger proteins contain DNA-binding domains and exhibit diverse biological functions, primarily in transcriptional regulation.
ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 or C16orf1, is a 485 amino acid multi-pass membrane protein with one DHHC-type zinc finger. It is expressed in fetal heart, lung, and kidney, as well as in adult lung and pancreas.
ZDHHC1 functions as a palmitoyltransferase, catalyzing the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA.
Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7, and ZDHHC18 also contain a DHHC-type zinc finger and exhibit palmitoyltransferase activity toward substrates such as H-Ras, SNAP25, and GABAA receptor proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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