Thermo Fisher Scientific CYP2C9 Monoclonal Antibody (OTI2C8), TrueMAB
CYP2C9 단백질을 인식하는 mouse monoclonal antibody로, Western blot, IHC, Flow cytometry에 사용 가능. 정제된 Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용. 약물 대사 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C8 |
| Immunogen | Full length human recombinant protein of human CYP2C9 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
The protein localizes to the endoplasmic reticulum, and its expression is induced by rifampin.
It metabolizes various xenobiotics, including phenytoin, tolbutamide, ibuprofen, and S-warfarin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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