Thermo Fisher Scientific Phospho-Fyn (Tyr531) Polyclonal Antibody
Fyn 단백질의 Tyr531 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적용 가능. 인간, 마우스, 랫트 반응성. 고순도 액상 형태로 -20°C 보관.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FYN (Accession P06241), corresponding to amino acid residues around phosphorylated Tyr531 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816229 |
Product Specific Information
Antibody detects endogenous levels of Fyn only when phosphorylated at Tyr531, which site historically referenced as Tyr530.
Target Information
FYN is a SRC-related kinase expressed in brain, skeletal muscle, and adipose tissues. Fyn functions in multiple cellular pathways and plays a role in memory. It is a member of the protein-tyrosine kinase oncogene family, encoding a membrane-associated tyrosine kinase involved in cell growth regulation. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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