Thermo Fisher Scientific Macro H2A.2 Polyclonal Antibody
Macro H2A.2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. Human에 반응하며 Mouse, Rat 등에서도 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 기반 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–197 of Macro H2A.2 (Uniprot ID: Q9P0M6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2552229 |
Product Specific Information
- Recommended positive control: human H2AFY2-transfected 293T
- Predicted reactivity: Mouse (97%), Rat (97%), Chicken (85%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription.
Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.
Histones thereby play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called the histone code, and nucleosome remodeling.
May be involved in stable X chromosome inactivation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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