Thermo Fisher Scientific TREM2 (extracellular) Polyclonal Antibody
Rabbit polyclonal antibody recognizing extracellular domain of TREM2. Validated for Western blot and flow cytometry. Supplied lyophilized, reconstitutable in water. Suitable for detecting TREM2 in mouse, human, and rat samples. For research use only.
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- PA5111856
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acid residues 42–56 of mouse TREM2 (Extracellular, N-terminus) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2857265 |
Product Specific Information
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4°C for up to one week. For longer periods, store small aliquots at -20°C. Avoid multiple freeze-thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Peptide sequence: (C)KHWGRRKAW(S)RQLGE
Homology: Mouse, human – 14/15 amino acid residues identical; rat – 12/15 amino acid residues identical.
Target Information
TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. It may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Mutations in this gene are associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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