Thermo Fisher Scientific SEPT4 Polyclonal Antibody
Thermo Fisher Scientific의 SEPT4 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 Rabbit IgG 기반 항체입니다. 다양한 응용(서던블롯, IHC, ICC, ELISA)에 적합하며, Protein A로 정제된 고순도 제품입니다. 연구용으로 세포사멸 관련 단백질 ARTS를 검출하는 데 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SEPT4, amino acids 91–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Apoptosis is related to many diseases and developmental processes. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis. A novel mitochondrial septin-like protein, designated ARTS (Apoptosis Related Protein in TGF-beta Signaling Pathway), was identified recently. ARTS, encoded by the human septin H5/PNUTL2/CDCrel2b gene, localizes to mitochondria and translocates to the nucleus during apoptosis. It is expressed in many tissues and enhances cell death induced by TGF-beta and, to a lesser extent, by TNF-a and Fas ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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