Thermo Fisher Scientific A1CF Polyclonal Antibody

Product Specifications

Product Specific Information

Immunogen sequence:
REIYMNVPVG AAGVRGLGGR GYLAYTGLGR GYQVKGDKRE DKLYDILPGM ELTPMNPVTL KPQGIKLAPQ ILEEICQ

Sequence identity:

• Mouse: 95%
• Rat: 81%

Target Information

Mammalian apolipoprotein B mRNA undergoes site-specific C-to-U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene.
The gene product has three non-identical RNA recognition motifs and belongs to the hnRNPR family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.