Thermo Fisher Scientific A1CF Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ACF if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:A1CF,uniProtId:Q9NQ94-1,ncbiNodeId:9606,antigenRange:380-456,antigenLength:594,antigenImageFileName:PA5-60608_A1CF_Q9NQ94-1_Rabbit.svg,antigenImageFileNamePDP:PA5-60608_A1CF_Q9NQ94-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637598

Product Specific Information

Immunogen sequence: REIYMNVPVG AAGVRGLGGR GYLAYTGLGR GYQVKGDKRE DKLYDILPGM ELTPMNPVTL KPQGIKLAPQ ILEEICQ

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 81%.

Target Information

Mammalian apolipoprotein B mRNA undergoes site-specific Cto U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and acomplementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNPR family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.