Thermo Fisher Scientific Phospho-MARCKS (Ser167, Ser170) Recombinant Rabbit Monoclonal Antibody (MARCKSS167170-C9), FITC
Phospho-MARCKS (Ser167, Ser170) 특이적 FITC 결합 재조합 단일클론 항체로, Flow Cytometry에 적합. Human, Mouse, Rat 반응성. HEK293 발현 시스템 기반 Rabbit IgG 형식. 세포 이동 및 신호전달 연구용. 단백질 A/G 정제, PBS+BSA 저장.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MARCKSS167170-C9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897372 |
Additional Formats
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and functions as an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and the plasma membrane, resulting in its presence in the cytoplasm. The protein is involved in cell motility, phagocytosis, membrane trafficking, and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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