Thermo Fisher Scientific PON2 Polyclonal Antibody
인간 PON2 단백질을 인식하는 염소 유래 폴리클로날 항체. IHC(P)에서 2–4 µg/mL 농도로 사용 가능. 항산화 및 세포 보호 연구에 적합하며, isoform 1과 2 모두를 인식. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ERLLALRNRLKAS (aa 19–31) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933192 |
Product Specific Information
- This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
The PON2 gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on chromosome 7q.
The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant protecting cells from oxidative stress.
Hydrolytic activity against acylhomoserine lactones suggests a role in defense responses to pathogenic bacteria.
Mutations in this gene may be associated with vascular disease and phenotypes related to diabetes.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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