Thermo Fisher Scientific Phospho-Aurora A/B/C (Thr288, Thr232, Thr198) Recombinant Rabbit Monoclonal Antibody (AuroraABC-CC12)
Aurora A/B/C 인산화 단백질(Thr288, Thr232, Thr198)을 인식하는 재조합 토끼 단일클론 항체. Flow Cytometry에 최적화. Protein A/G 정제, PBS 기반 보존. 세포 분열 및 시토키네시스 연구용.
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Applications
- Flow Cytometry (Flow): 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | AuroraABC-CC12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding human Aurora A (Thr288), Aurora B (Thr232), Aurora C (Thr198) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol, 0.10% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897332 |
Additional Formats
Target Information
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a key regulator of mitosis. The CPC ensures proper chromosome alignment and segregation, and is essential for spindle assembly and cytokinesis. It phosphorylates multiple substrates including INCENP, BIRC5, CDCA8, and histone H3, regulating chromatin condensation and cytokinetic processes. Aurora kinases are critical for cell cycle progression and genomic stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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