Thermo Fisher Scientific Formyl-HIST1H2BC (Lys5) Polyclonal Antibody
Thermo Fisher Scientific의 Formyl-HIST1H2BC (Lys5) 폴리클로날 항체는 인간 시료에 반응하며, ICC/IF 및 ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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- PA5121413
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:10–1:100 | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (2–13aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.14 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2914985 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction.
This protein also exhibits antibacterial and antifungal activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone belonging to the H2B family. It lacks a polyA tail but contains a palindromic termination element. This gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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