Thermo Fisher Scientific FGF4 Monoclonal Antibody (2D7D5)
FGF4 단백질을 인식하는 Mouse IgG1 단클론 항체로, 인간 시료에 반응합니다. Western blot, Flow cytometry, ELISA 등 다양한 분석에 사용 가능하며, ELISA에서 1:10,000 희석으로 검증되었습니다. 연구용으로만 사용되며 FGF4 관련 세포 성장 및 분화 연구에 적합합니다.
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Thermo Fisher Scientific FGF4 Monoclonal Antibody (2D7D5)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D7D5 |
| Immunogen | Purified recombinant fragment of human FGF4 (AA: 62–123) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2787357 |
Product Specific Information
MA5-31733 has been tested in indirect ELISA.
Target Information
Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possesses broad mitogenic and cell survival activities. It plays key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis.
FGF4 is a potent angiogenic factor expressed in several highly vascularized tumors and in adult mouse testis, intestine, and brain.
Studies on the mouse homolog suggest a role in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a feedback inhibition mechanism by a novel FGF4 splice isoform that may promote differentiation at later stages of development.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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